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Recombinant human DR6 (TNFRSF21)/Fc Chimera

	Product No.	Form	Quantity	Stock	Price	Datasheet
	RL-003-C050	Lyophilized	0.05 mg		290 EUR

- In stock! Ready for immediate despatch

- Manufacture on order

Source

Produced in HEK 293 cells. The extracellular domain of human DR6 (aa 1 - 212) is fused to the Fc portion of human IgG1.

Description

Human DR6 (Death Receptor-6; TNFRSF21) is a type I transmembrane protein containing cytoplasmic death domain, member of the TNF receptor superfamily, expressed in most human tissues.

Database Links

Applications:

Loading control
The recombinant human DR6/Fc chimera can be used as a control for anti-human DR6 antibodies in amounts 15-50 ng.

Usage note:
Indicated dilutions are recommended starting points for use of this product. Working concentrations should be determined by the investigator.

General references

Pan G. et al., Identification and functional characterization of DR6, a novel death domain-containing TNF receptor. FEBS Lett. 1998 431(3):351-6. [Abstract]

For research use only. Not for drug, diagnostic or other use.

Related Products

Mouse Monoclonal to CD358 / DR6 DR-6-04-EC (IgG1)

Example Data

Fig. 1. SDS-PAGE

Fig.1. SDS-PAGE Electrophoresis of DR6 / Fc recombinant protein (12% separating gel, 6% stacking gel; reducing conditions).
Lane 1 to 5: DR6 / Fc recombinant protein (2000 ng, 1000 ng, 500 ng, 200 ng, 100 ng per lane). Staining with Coomasie Blue.

Fig. 2. Western Blotting

Fig.2. Western blotting of DR6 / Fc recombinant protein. Reducing conditions.
Lane 1 to 4: immunostaining with rabbit polyclonal antibody specific to DR6 (EC). Detection with Goat anti-rabbit / HRP secondary antibody. Amount of DR6 / Fc recombinant protein loaded on each lane: (1) 150 ng, (2) 75 ng, (3) 30 ng, (4) 15 ng per lane.